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  8. 15195624

Thermo Scientific™ pH Gradient Buffer Concentrates

Robust reproducible gradients that are applicable to a wide range of MAbs and ready to use with existing LC columns and systems, without the need to formulate mobile phases.

Brand:  Thermo Scientific™ 083381

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Product Code. 15195624

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Beskrivning

Beskrivning

Obtain fast and highly robust, reproducible HPLC gradients using Thermo Scientific™ CX-1 pH Gradient Buffers. Simple to optimize and easily automated, these buffers are applicable for HPLC separation of the majority of monoclonal antibody (mAb) biotherapeutics drugs. CX-1 pH Gradient Buffers are ready to use with existing HPLC columns without the need to formulate mobile phases. The CX-1 buffers save time in method development, facilitate method transfer to QA/QC for a wide range of mAb charge variants through a generic HPLC-based approach to mAb characterization, and do not require time-consuming mobile phase adjustments.

pH buffer solutions can be used to generate highly reproducible, linear pH gradients in cation exchange chromatography.

  • Robust, reproducible gradients
  • Predict biomolecule pH
  • Simple method optimization
  • Easily automated
  • Applicable to the majority of MAbs

Unlike traditional cation exchange chromatography using salt gradients, it is possible to predict the pH and the expected retention of the charge variants and use a narrow pH range to get a higher resolution separation.

TRUSTED_SUSTAINABILITY
Specifikationer

Specifikationer

CX-1 pH Gradient Starter Kit, Buffer A + Buffer B
CX-1 pH Gradient Starter Kit
5.6 to 10.2
Thermo Scientific
LC Columns and Systems
MAbPac SCX-10 Column (10 μm, 4 x 250 mm)
125 mL + 125 mL
Produktförslag

Produktförslag

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